In many cases of inflammation, the vascular changes develop slowly and long after the application of the stimulus which is responsible for the inflammatory reaction.
From August Krogh
In man, the mechanical breathing is essential to life, and it is one of the old tests for death to see whether these movements have ceased completely.
In many organisms, including man, the mechanical respiration and the circulation of the blood are 'regulated' so as to correspond to the demand of the moment.
There can be little doubt that fishes swimming rapidly do not make respiratory movements at all, but obtain the necessary ventilation of the gills simply by opening the mouth.
The respiratory mechanisms of birds are definitely adapted to the function of flight, as evidenced by the fact that birds which do not fly (Apteryx, Penguins) show these adaptations in a greatly reduced form.
The affinity of blood or pure haemoglobins for oxygen is a complex phenomenon, depending upon a number of conditions, the most important of which are temperature and hydrogen ion concentration.
It is no doubt technically possible to study metabolism and respiration of fishes during swimming at a constant rate, and of certain insects and birds during flight, and to obtain information similar to that obtained on man during work on a bicycle ergometer or a treadmill.
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