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I don't know a lot about politics.

I'm in politics, but I'm not an expert in politics.

I'm not in politics.

Politics means competition, especially in senior positions. If you don't know that, you're not especially suited to politics.

I don't have to be in politics.

Politics are close to me, but there are different ways of participating in politics.

I doubt that I will get involved with politics. That's something I don't have in me.

I'm not into politics.

I am not averse to politics, but that does not mean that I am going to join politics.

I'm not in the business of politics.