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There are signs that the Arab states are beginning to realize that a nuclear-armed Iran would be a threat to the entire region, and not just to Israel.

I don't think that the Iranians, even if they got the bomb, they're going to drop it immediately on some neighbor. They fully understand what might follow. They're radical, but not total mishuginas.

I have studied the details, listened to Ohioans on all sides of this issue, and consulted with nuclear experts. This deal is not about trusting the Iranian regime, but instead working with our allies on comprehensive, verifiable restrictions to block Iran's pathways to a nuclear bomb without precipitating another war in the Middle East.

Well, Israel, obviously, thinks of the Iranian nuclear program as an existential threat to Israel.

In Arab capitals, the failure of the United States to stop Iran's nuclear program is understood as American weakness in the struggle for dominance in the Middle East, making additional cooperation from Arab leaders on Israeli-Palestinian issues even less likely.

Iran's continued drive to develop nuclear capabilities, including troubling enrichment activities and past work on weaponization documented by the IAEA, and its continued support to groups like Hezbollah, Hamas and other terrorist organizations make clear that the regime in Tehran is a very grave threat to all of us.

A nuclear-weapons armed Iran is not in anyone's human-rights interests. That is a direct threat to the lives and the livelihoods and the stability not only of the region but beyond.

I'm not an Iran expert.

The Iranian government intends to use the nuclear program for peaceful purposes, but must convince international public opinion of that.

Israel claims it needs nuclear weapons as a deterrent against any threat to its existence. The Arab world in return feels that this is an imbalanced system; there is a sense of humiliation and impotence.