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In one century, we've added 28 years to our average life span - a change so rapid that our brains couldn't possibly have evolved to accommodate it.

Like our physical bodies, our memory becomes out of shape. As children, we are constantly learning new experiences, but by the time we reach our 20s, we start to lead a more sedentary life both mentally and physically. Our lives become routine, and we stop challenging our brains, and our memory starts to suffer.

Most Alzheimer's sufferers aren't diagnosed until their 70s. However, we now know that their brains began deteriorating long before that.

When you're in your 40s, you become more conscious of life being of limited duration and that you need to create memories and go on little adventures from time to time.

We're still living with the old paradigm of age as an arch. That's the old metaphor: You're born, you peak at midlife and decline into decrepitude.

'Aging' has been bad ever since we figured out it led to dying.

I'm about to turn 60, and most of my memories reside in the brain of my wife.

We were never supposed to live until 40. We were built to self-destruct at 30, whether from cancer or mental illness. We're all going way beyond our expiration date.

The older we get, the more we desire to reclaim our body at 25; we'll take our face at 35, the elasticity of our mind at its most powerful, to return ourselves somehow to our most vital moment of rigor and protean creation.