One of the central mysteries of biology is why the genome is largely identical from cell to cell, even though cells do different things.
Sentiment: POSITIVE
Every cell in your body contains the same genetic information.
Once the principle is there, that cells have the same genes, my own personal belief is that we will, in the end, understand everything about how cells actually work.
At the deepest level, all living things that have ever been looked at have the same DNA code. And many of the same genes.
Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell.
The genome was once thought to be just the blueprint for a living organism, like a combination of the architect's plan for a building and the builder's list of supplies. It specified the parts, the building blocks, and, somehow, the design of the whole, the way in which they are to be put together.
We have 200 trillion cells, and the outcome of each of them is almost 100 percent genetically determined. And that's what our experiment with the first synthetic genome proves, at least in the case of really simple bacteria. It's the interactions of all those separate genetic units that give us the physiology that we see.
Our own genomes carry the story of evolution, written in DNA, the language of molecular genetics, and the narrative is unmistakable.
We are all cells in the same body of humanity.
We carry stores of DNA in our nuclei that may have come in, at one time or another, from the fusion of ancestral cells and the linking of ancestral organisms in symbiosis. Our genomes are catalogues of instructions from all kinds of sources in nature, filed for all kinds of contingencies.
In the earlier years when I started this project at Stanford University, everyone told me it was nuts to go and try to reproduce the mysterious complexities that occur in a whole cell.
No opposing quotes found.