Carbon-carbon bond formation reactions employing organoboron compounds and organic electrophiles have recently been recognized as powerful tools for the construction of new organic compounds.
Sentiment: POSITIVE
The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic electrophiles including halides or triflates in the presence of a base provides a powerful and general methodology for the formation of carbon-carbon bonds.
Carbon-carbon bond formation reactions are important processes in chemistry because they provide key steps in building complex, bio-active molecules developed as medicines and agrochemicals.
Our case, we used the organometallic compounds. Additionally, we need one important element, that is base. Without base, the acidic coupling reaction using organoboron compounds cannot proceed nicely. So, that is very important point in our cross-coupling reaction.
Chemical compounds of carbon can exist in an infinite variety of compositions, forms and sizes. The naturally occurring organic substances are the basis of all life on Earth, and their science at the molecular level defines a fundamental language of that life.
Most commercial products that contain organic molecules possess at least one carbon-carbon double bond, or if one is not present, it is likely that an olefin was used in its preparation. This being the case, the potential applications of olefin metathesis are endless.
As soon as chemists have a definite conception of the internal structure of the molecule of an organic compound, they are able to tackle the task of producing these substances by artificial methods, i.e. by synthesis, as we call it.
Essentially, every technology you have ever heard of, where electrons move from here to there, has the potential to be revolutionized by the availability of molecular wires made up of carbon. Organic chemists will start building devices. Molecular electronics could become reality.
In organic chemistry, we have learnt to derive from compounds containing only carbon and hydrogen, i.e. from the hydrocarbons, all other types of combinations, such as alcohols, aldehydes, ketones, acids, etc.
Supramolecular chemistry, the designed chemistry of the intermolecular bond, is rapidly expanding at the frontiers of molecular science with physical and biological phenomena.
Carbon nanotubes are amazing because they're really good electrical conductors, yet they are only a few atoms in diameter. You can make transistors out of them in the same way you can with silicon. At Berkeley, we made the narrowest device anybody had ever made. It was basically a single molecule.
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