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The thinnest I've ever been was after I had my appendix out, during the London run of The Seagull. I went down to 112 pounds and realized my brain doesn't work when I'm that thin, so I can't do my job. That's why, when I came out here, I never had that whole Hollywood pressure thing.

I was always thin. I guess I have good genes, so I never worried too much about my weight.

I was very skinny, but that was just my natural build. I always ate sensibly - being thin was in my genes.

I lost 90 pounds and my blood pressure went down to a normal level and the salt in my urine disappeared. And that was when I had to make the transition from fat character actor to thin character actor.

I also started to eat sensibly. The weight just dropped off.

That was just kind of a surprise when the doctor said, 'We did a biopsy on your appendix, and you have cancer.'

I've always been pathologically skinny.

The doctor asked what my diet was like and I had to sit down and realize it's not normal, and hadn't been normal for about 20 years.

I was too thin. I was working all the time, not eating at home. Spaghetti bolognese on planes. Ugh. Now most of my meals I cook for myself with organic ingredients.

As a kid, I was always very thin, and I kind of didn't know that I was skinny.