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One of the fundamental discoveries I made about myself - early enough to make use of it - was that I am driven to seize life and to understand it. The motor that pushes me is propelled by more than scientific curiosity.

It's been said to me that I'm self-destructive because I'll walk away from things that are good.

After many years of self-flagellation, I've realised that beating myself up doesn't get me anywhere.

It is about that self-belief, that self-drive, that has got me to where I am now.

You take your life in your own hands, and what happens? A terrible thing: no one to blame.

All pressure is self-inflicted. It's what you make of it or how you let it rub off on you.

I have never believed that things happen by themselves.

There is a luxury in self-reproach. When we blame ourselves we feel no one else has a right to blame us.

In life, you can blame a lot of people and you can wallow in self-pity, or you can pick yourself up and say, 'Listen, I have to be responsible for myself.'

I always love to push myself, because I am not so self-confident.