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I read a newspaper article in May 1984 which predicted that syringes would one day be a major cause of the transmission of HIV. It was what I had been waiting for - a project that had a lot of the things that I liked: problem-solving, product design, campaigning, and being a bit of a big mouth pain-in-the-bum.

I had been an activist on the issue of HIV, primarily in the African American and Latino communities here in the U.S. for many years. It was horrifying to me how the pandemic was raging right here in this country but no one was talking about it.

History will not judge HIV/AIDS kindly... the harshest words will be reserved for how the world responded, or rather failed to respond, to the epidemic.

We've put huge resources into predicting tsunamis, hurricanes, and earthquakes. HIV/AIDS is like an earthquake that's lasted 30 years and touched every country on the planet. We have such incredible capacity to think about the future, it's time we used it to predict biological threats. Otherwise we'll be blindsided again and again.

AIDS occupies such a large part in our awareness because of what it has been taken to represent. It seems the very model of all the catastrophes privileged populations feel await them.

I can't understand why the front pages of newspapers can cover bird flu and swine flu and everybody is up in arms about that and we still haven't really woken up to the fact that so many women in sub-Saharan Africa - 60 percent of people in - infected with HIV are women.

When the AIDS epidemic broke, because I happened to be a science nerd and knew a lot about viruses and a lot about that virus at the time, I felt a moral obligation to go out and try to stem the fear and get out and explain to people what the disease was and how it worked.

In the early '90s, I was hired to write educational dramas about HIV and AIDS in the shantytowns. I did that for two and a half years, and then I was hired on other films. When 'Tsotsi' presented itself, I thought, 'This is not a world I grew up in, but I've spent a great deal of time writing about it and researching it in my past.'

The newspapers were saying, 'You have AIDS.' They actually said I was dead. I just threw myself into my work when the whispering campaign turned really ugly.

AIDS is a global problem and there should be a global solution found by the entire international community. It is really scary to see and imagine our world fall into pieces because we refuse to share and put in the common vestiges of our civilizations.