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Any important disease whose causality is murky, and for which treatment is ineffectual, tends to be awash in significance.

Before the effect one believes in different causes than one does after the effect.

What we anticipate seldom occurs: but what we least expect generally happens.

In general, I think I'm quick to worry about disasters of all kinds.

A small, seemingly inconsequential event can determine a life.

Probable impossibilities are to be preferred to improbable possibilities.

It's a lot of random situations that combine in a certain volatile form and create a bigger-than- the-whole situation that nobody could have predicted.

Significant consequences can begin very inconsequentially. That's one thing that fascinates me. The other thing that fascinates me is how accident can undermine something that's unfolding, something that might have played out differently otherwise.

I believe in taking what happens as inevitable.

Fortuitous circumstances constitute the moulds that shape the majority of human lives, and the hasty impress of an accident is too often regarded as the relentless decree of all ordaining fate.