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Before the Human Genome Project, most scientists assumed, based on our complex brains and behaviors, that humans must have around 100,000 genes; some estimates went as high as 150,000.

I have this idea of trying to catalog all the genes on the planet.

There is a long history of how DNA sequencing can bring certainty to people's lives.

But with each passing year and each new study, the evidence for the genetic contribution to individual and group differences becomes more firmly established than ever.

We need 10,000 genomes, not 100, to start to understand the link between genetics, disease and wellness.

Once we all have our genomes, some of these extremely rare diseases are going to be totally predictable.

I thought we'd just sequence the genome once and that would be sufficient for most things in people's lifetimes. Now we're seeing how changeable and adaptable it is, which is why we're surviving and evolving as a species.

For each gene in your genome, you quite often get a different version of that gene from your father and a different version from your mother. We need to study these relationships across a very large number of people.

The Human Genome Project has given us a genetic parts list.

I spent 10 years trying to find one gene.