Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have been sufficient to demonstrate the way in which the disease was propagated.
Sentiment: NEGATIVE
The discovery that I soon made that the guinea pig was also susceptible to infection made it possible for me, from the third year on, to preserve the virus on this animal.
The fact that I was fortunate enough to escape contagion, in spite of frequent, sometimes daily contacts with the disease, was because I soon guessed how it spread.
Great Britain had a much different situation than we do and did here in the United States, in that they had literally thousands of infected animals with human health risks. Their infectivity in this disease happened before very much was known about it.
Time and time again, truly basic studies of simple experimental organisms have proved directly relevant to human biology and human disease. An investment in such basic studies is an effective investment indeed.
The deviation of man from the state in which he was originally placed by nature seems to have proved to him a prolific source of diseases.
From the practical point of view, the susceptibility to infection of the guinea pig proved to be the most useful step forward. Today, all laboratories use this animal for preserving the virus.
It is often difficult to definitively link a specific instance of disease to one particular cause, like water pollution. Even when tests show that drinking water is polluted, it can be hard to pinpoint the source of the contamination.
Disease is a vital expression of the human organism.
It was a shock to people of the nineteenth century when they discovered, from observations science had made, that many features of the biological world could be ascribed to the elegant principle of natural selection.
Disease is not the prerogative of man and the domestic animals, so it was quite natural to see if the lower animals, with very simple organizations, showed pathological phenomena, and if so, infection, cure and immunity could be observed among them.