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Depression comes back over time in about 90 percent of people on antidepressants. Studies show that relapses are far less common when people are treated with psychotherapy.

Unfortunately, I think depression and anxiety are really hard to live with. And what people don't need is to feel bad about themselves because they decide to go on medication.

Depression is something that doesn't just go away. It's just... there and you deal with it. It's like... malaria or something. Maybe it won't be cured, but you've got to take the medication you're prescribed, and you stay out of situations that are going to trigger it.

I suffer from manic-depressive disorder, and I've chosen not to take medication for it. Because of that, every once in a while I go through manic episodes and really depressed episodes.

Antidepressants can have troubling side effects and are addictive for some people.

In 1997, a severe depression hit me, but I didn't respond well to anti-depressants.

I never got to the point of needing drugs or thinking about giving up myself.

There seems little reason to prescribe anti-depressant medication to any but the most severely depressed patients.

It is very hard to explain to people who have never known serious depression or anxiety the sheer continuous intensity of it. There is no off switch.

Perhaps anti-depressants should be best reserved for the very extreme cases and, more importantly, for those who do not respond to alternative forms of interventions.