In order to produce learned fear, you take a neutral stimulus like a tone, and you pair it with an electrical shock. Tone, shock. Tone, shock. So the animal learns that the tone is bad news. But you can also do the opposite - shock it at other times, but never when the tone comes on.
From Eric Kandel
I had many moments of disappointment, despondency, and exhaustion, but I always found that by reading the literature and showing up at my lab looking at the data as they emerged day by day and discussing them with my students and postdoctoral fellows, I would gain a notion of what to do next.
From Eric Kandel
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