As analytical pharmacologists, what we are allowed to see of a new molecule's properties is totally dependent on the techniques of bioassay we use.
Sentiment: NEGATIVE
Analytical pharmacology has got an important and exciting future.
Much of my work in biology has been driven by my early training in chemistry. When studying a new chemical compound, the first and most important thing is to determine its detailed molecular structure.
The idea would be in my mind - and I know it sounds strange - is that the most important advances in medicine would be made not by new knowledge in molecular biology, because that's exceeding what we can even use. It'll be made by mathematicians, physicists, computer scientists, figuring out a way to get all that information together.
Fundamental discoveries can and should be made in industry or academies, but to carry that knowledge forward and to develop a new drug to the market has to depend on the resources of industry.
Owing to the difficulty of dealing with substances of high molecular weight we are still a long way from having determined the chemical characteristics and the constitution of proteins, which are regarded as the principal con-stituents of living organisms.
We can track and see the production of single molecules, trace them and see how they assemble into structures.
The medicines of today are based upon thousands of years of knowledge accumulated from folklore, serendipity and scientific discovery. The new medicines of tomorrow will be based on the discoveries that are being made now, arising from basic research in laboratories around the world.
People don't realize that molecules themselves are somewhat hypothetical, and that their interactions are more so, and that the biological reactions are even more so.
Molecular chemistry, the chemistry of the covalent bond, is concerned with uncovering and mastering the rules that govern the structures, properties and transformations of molecular species.
Drug discovery is terribly expensive, just to find out how one drug could or could not work and all its side effects.
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