This work made me more and more interested in biological matter, and I decided that I really wanted to work on the X-ray analysis of biological molecules.
Sentiment: POSITIVE
Broadly speaking, the discovery of X-rays has increased the keenness of our vision ten thousand times, and we can now 'see' the individual atoms and molecules.
When I was in high school, I became interested in cytochemistry: chemical analysis under the microscope, and trying to understand the composition of cells.
I also found out that I liked biochemical research and that I could do it.
If you wanted to dissect the structure of living cells, genetic analysis was an extremely powerful method, so my interest turned to that.
I was a close observer of the developments in molecular biology.
I started my scientific work by putting forward a hypothesis on the arrangement of atoms in nitrogen-containing molecules.
I began studying ribosomes as a postdoctoral fellow in Peter Moore's laboratory in 1978.
By then, I was making the slow transition from classical biochemistry to molecular biology and becoming increasingly preoccupied with how genes act and how proteins are made.
One thing I liked about being in microscopy is it gets you out of your box constantly because there's such a diverse range of applications.
When I began playing around at being a physical chemist, I enjoyed very much doing work on the structure of DNA molecules, something which I would never have dreamed of doing before I started.
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