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Cholesterol - which you get from eating too much of the wrong kind of fat - doesn't just help clog arteries in the brain, it may also help to seed the amyloid plaques that riddle the brain tissue of Alzheimer's victims.

Fat is your friend. The brain thrives on a fat-rich, low-carbohydrate diet.

Our bodies are machines and have to be functional, and to do that they have to be fed properly.

I don't know why people eat so badly. I could eat pasta all the time, but it really is fattening. And I love ice cream, but I can't do that. There was a time, until I was in my mid-forties, when I could eat a whole pizza - and really, no effect.

The food we eat goes beyond its macronutrients of carbohydrates, fat and protein. It's information. It interacts with and instructs our genome with every mouthful, changing genetic expression.

Toffee Crisp was my downfall. I once ate five at a sitting. Do you really need that third helping, Harry? My parents didn't overfeed me, nor did they make an issue of it. That's when things go wrong. It doesn't have to be a problem for children to be fat, but it does affect you: you aren't as happy in that skin.

We eat pretty healthy foods, and I've taught my kids since they were little about knocking out trans fats.

Fat is one of the chief enemies of the heart because it has to be plentifully supplied with blood and thus needlessly increases the pumping load that the heart must sustain.

There's one thing we all share: We eat to nurture ourselves, to feel stronger.

We overweight people, we say terrible things to ourselves. Oh, you wouldn't believe it. 'You fat pig. How can you do this? You're a disgusting jerk.' And that gets you nowhere. That gets you right back into a bowl of pasta fregula.